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To reduce the development of drug-resistant bacteria and maintain the effectiveness of ZYVOX and other antibacterial drugsZYVOX should be used only to treat or prevent infections that are proven or strongly suspected to be caused by susceptible bacteriaWhen culture and susceptibility information are availablethey should be considered in selecting or modifying antibacterial therapyIn the absence of such datalocal epidemiology and susceptibility patterns may contribute to the empiric selection of therapy.

Zyvox is indicated in adults for the treatment of community acquired pneumonia and nosocomial pneumonia when known or suspected to be caused by susceptible Gram positive bacteriaIn determining whether Zyvox is an appropriate treatmentthe results of microbiological tests or information on the prevalence of resistance to antibacterial agents among Gram positive bacteria should be taken into considerationsee section 5.1 for the appropriate organisms

Consideration should be given to official guidance on the appropriate use of antibacterial agents.

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